About GenEros

Founder Dr. Xin-Yuan Fu

A world well-known scientist in molecular biology, biochemistry, and medicine and an experienced entrepreneur.

1982Graduate student of the world-renowned geneticist Dr. C.C. Tan of Fudan University.

1982First class of CUSBEA (China-US China–United States Biochemistry Examination and Application) scholar.

1982-1988Ph. D. student of Columbia University in molecular biology.  (Adviser:James Manley)

1988-1991Post-doctoral fellow of Rockefeller University. (Adviser:James Darnell)

1992-1994Assistant professor of Mount Sinai School of Medicine.

1994-2003Associate professor of pathology and immunology of Yale University School of Medicine.

1996-2003Committee Chairman of Medical Doctors in pathology of Yale University.

2004-2015Professor of immunology of Indiana University.

1999-2006Director of Institute of Human Genetics of Tsinghua University.

2008-2018Director and professor of Biochemistry Department, National University of Singapore School of Medicine.

The most important discovery of Dr. Fu is the JAK-STAT signal transduction pathway and its importance in life and diseases. The JAK-STAT pathway was discovered in 1993 and was named as one of the most important scientific discoveries of the year by the journal of Science. 

Dr. Fu’s laboratory at the National University of Singapore discovered a new mechanism of immunoregulation: a Th-GM subclass of T Helper cells, whose dysregulation is the origin of inflammations and a target for medical treatments. This discovery also revealed functions and mechanisms of JAK-STAT signaling in cancer, cardiovascular disease, neurodegeneration, aging, and tissue regeneration. 

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